1. High purity and high yield: The product configuration can be accurately controlled by chemical synthesis to obtain L-menthol with high optical purity, avoiding the problems of many impurities and cumbersome separation in natural extraction. The yield of some synthetic routes (e.g., melt crystallization splitting) can reach 99%, which is significantly better than the low yield of natural extraction.  

2. Feasibility of large-scale production: The chemical synthesis method is not limited by plant raw materials, and can be produced on a large scale through industrial processes to meet the high global demand for L-menthol (such as spices, pharmaceuticals and other fields). For example, the combination of the split method and the continuous melt crystallization technology can achieve efficient splitting and continuous production.  

3. Cost-effective advantages: The raw materials of the synthetic route are easy to obtain, the steps are controllable, and the comprehensive cost is lower than that of the natural extraction method (which requires a large number of mint leaves and the extraction process is complex). Directed synthesis also reduces by-products and purification costs.  

4. Superior application performance Synthetic L-menthol has the characteristic cooling effect and physiological activity of natural peppermint oil, and has significant effects in nerve block, analgesic, bactericidal and other fields, and its application value is higher than that of D-menthol. Its derivatives (such as menthyl lactate) have the properties of non-irritating and long-term cooling.